CIP2A regulates MYC translation (via its 5′UTR) in colorectal cancer

BACKGROUND: Deregulated expression of MYC is a driver of colorectal carcinogenesis, suggesting that decreasing MYC expression may have significant therapeutic value. CIP2A is an oncogenic factor that regulates MYC expression. CIP2A is overexpressed in colorectal cancer (CRC), and its expression leve...

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Publicat a:Int J Colorectal Dis
Autors principals: Denk, S., Schmidt, S., Schurr, Y., Schwarz, G., Schote, F., Diefenbacher, M., Armendariz, C., Dejure, F., Eilers, M., Wiegering, Armin
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2020
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8178152/
https://ncbi.nlm.nih.gov/pubmed/33078202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00384-020-03772-y
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