CIP2A regulates MYC translation (via its 5′UTR) in colorectal cancer

BACKGROUND: Deregulated expression of MYC is a driver of colorectal carcinogenesis, suggesting that decreasing MYC expression may have significant therapeutic value. CIP2A is an oncogenic factor that regulates MYC expression. CIP2A is overexpressed in colorectal cancer (CRC), and its expression leve...

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Detalhes bibliográficos
Publicado no:Int J Colorectal Dis
Main Authors: Denk, S., Schmidt, S., Schurr, Y., Schwarz, G., Schote, F., Diefenbacher, M., Armendariz, C., Dejure, F., Eilers, M., Wiegering, Armin
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8178152/
https://ncbi.nlm.nih.gov/pubmed/33078202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00384-020-03772-y
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