Acquisition of protease resistance by prion proteins in scrapie-infected cells does not require asparagine-linked glycosylation.

The scrapie and cellular isoforms of the prion protein (PrPSc and PrPC) differ strikingly in a number of their biochemical and metabolic properties. The structural features underlying these differences are unknown, but they are thought to result from a posttranslational process. Both PrP isoforms co...

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Bibliografiske detaljer
Main Authors: Taraboulos, A, Rogers, M, Borchelt, D R, McKinley, M P, Scott, M, Serban, D, Prusiner, S B
Format: Artigo
Sprog:Inglês
Udgivet: 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC54935/
https://ncbi.nlm.nih.gov/pubmed/1978322
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