Acquisition of protease resistance by prion proteins in scrapie-infected cells does not require asparagine-linked glycosylation.
The scrapie and cellular isoforms of the prion protein (PrPSc and PrPC) differ strikingly in a number of their biochemical and metabolic properties. The structural features underlying these differences are unknown, but they are thought to result from a posttranslational process. Both PrP isoforms co...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1990
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54935/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1978322/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.21.8262 |
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