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Attempts to convert the cellular prion protein into the scrapie isoform in cell-free systems.

The scrapie prion protein (PrPSc) is derived from a cellular isoform (PrPC) that acquires protease resistance posttranslationally. We have used several different experimental approaches in attempts to reconstitute in vitro the processes leading to protease-resistant PrPSc molecules. In the first stu...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Raeber, A J, Borchelt, D R, Scott, M, Prusiner, S B
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1992
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC283664/
https://ncbi.nlm.nih.gov/pubmed/1356161
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