Attempts to convert the cellular prion protein into the scrapie isoform in cell-free systems.
The scrapie prion protein (PrPSc) is derived from a cellular isoform (PrPC) that acquires protease resistance posttranslationally. We have used several different experimental approaches in attempts to reconstitute in vitro the processes leading to protease-resistant PrPSc molecules. In the first stu...
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| I publikationen: | J Virol |
|---|---|
| Huvudupphov: | , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
American Society for Microbiology (ASM)
1992
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283664/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1356161/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.10.6155-6163.1992 |
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