Acquisition of protease resistance by prion proteins in scrapie-infected cells does not require asparagine-linked glycosylation.

The scrapie and cellular isoforms of the prion protein (PrPSc and PrPC) differ strikingly in a number of their biochemical and metabolic properties. The structural features underlying these differences are unknown, but they are thought to result from a posttranslational process. Both PrP isoforms co...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Taraboulos, A, Rogers, M, Borchelt, D R, McKinley, M P, Scott, M, Serban, D, Prusiner, S B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54935/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1978322/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.21.8262
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