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The Canonical Notch Signaling Pathway: Structural And Biochemical Insights Into Shape, Sugar, And Force
The Notch signaling pathway relies on a proteolytic cascade to release its transcriptionally active intracellular domain, on force to unfold a protective domain and permit proteolysis, on extracellular domain glycosylation to tune the forces exerted by endocytosed ligands, and on a motley crew of nu...
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| Publicado no: | Dev Cell |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5492985/ https://ncbi.nlm.nih.gov/pubmed/28486129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2017.04.001 |
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