Structure of the full-length glucagon class B G protein-coupled receptor

The human glucagon receptor (GCGR) belongs to the class B G protein-coupled receptor (GPCR) family and plays a key role in glucose homeostasis and the pathophysiology of type 2 diabetes. Here we report the 3.0 Å crystal structure of full-length GCGR containing both extracellular domain (ECD) and tra...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Nature
मुख्य लेखकों: Zhang, Haonan, Qiao, Anna, Yang, Dehua, Yang, Linlin, Dai, Antao, de Graaf, Chris, Reedtz-Runge, Steffen, Dharmarajan, Venkatasubramanian, Zhang, Hui, Han, Gye Won, Grant, Thomas D., Sierra, Raymond G., Weierstall, Uwe, Nelson, Garrett, Liu, Wei, Wu, Yanhong, Ma, Limin, Cai, Xiaoqing, Lin, Guangyao, Wu, Xiaoai, Geng, Zhi, Dong, Yuhui, Song, Gaojie, Griffin, Patrick R., Lau, Jesper, Cherezov, Vadim, Yang, Huaiyu, Hanson, Michael A., Stevens, Raymond C., Zhao, Qiang, Jiang, Hualiang, Wang, Ming-Wei, Wu, Beili
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2017
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5492955/
https://ncbi.nlm.nih.gov/pubmed/28514451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22363
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

समान संसाधन