In Vitro Activity and Mechanism of Action of Methylenecyclopropane Analogs of Nucleosides against Herpesvirus Replication

We have reported previously that methylenecyclopropane analogs of nucleosides have excellent activity against certain members of the herpesvirus family. A second generation, the 2,2-bis-hydroxymethyl derivatives, were synthesized, and 18 compounds were tested for activity in vitro against herpes sim...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Kern, Earl R., Kushner, Nicole L., Hartline, Caroll B., Williams-Aziz, Stephanie L., Harden, Emma A., Zhou, Shaoman, Zemlicka, Jiri, Prichard, Mark N.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2005
Предметы:
Antiviral Agents
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC549243/
https://ncbi.nlm.nih.gov/pubmed/15728900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.3.1039-1045.2005
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы