In Vitro Activity and Mechanism of Action of Methylenecyclopropane Analogs of Nucleosides against Herpesvirus Replication

We have reported previously that methylenecyclopropane analogs of nucleosides have excellent activity against certain members of the herpesvirus family. A second generation, the 2,2-bis-hydroxymethyl derivatives, were synthesized, and 18 compounds were tested for activity in vitro against herpes sim...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Antimicrob Agents Chemother
Egile Nagusiak: Kern, Earl R., Kushner, Nicole L., Hartline, Caroll B., Williams-Aziz, Stephanie L., Harden, Emma A., Zhou, Shaoman, Zemlicka, Jiri, Prichard, Mark N.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2005
Gaiak:
Antiviral Agents
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC549243/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15728900/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.49.3.1039-1045.2005
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