Ubiquitin ligase RNF146 coordinates bone dynamics and energy metabolism

Cleidocranial dysplasia (CCD) is an autosomal dominant human disorder characterized by abnormal bone development that is mainly due to defective intramembranous bone formation by osteoblasts. Here, we describe a mouse strain lacking the E3 ubiquitin ligase RNF146 that shows phenotypic similarities t...

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Bibliografiset tiedot
Julkaisussa:J Clin Invest
Päätekijät: Matsumoto, Yoshinori, La Rose, Jose, Lim, Melissa, Adissu, Hibret A., Law, Napoleon, Mao, Xiaohong, Cong, Feng, Mera, Paula, Karsenty, Gerard, Goltzman, David, Changoor, Adele, Zhang, Lucia, Stajkowski, Megan, Grynpas, Marc D., Bergmann, Carsten, Rottapel, Robert
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2017
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5490759/
https://ncbi.nlm.nih.gov/pubmed/28581440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI92233
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