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RANKL coordinates multiple osteoclastogenic pathways by regulating expression of ubiquitin ligase RNF146
Bone undergoes continuous remodeling due to balanced bone formation and resorption mediated by osteoblasts and osteoclasts, respectively. Osteoclasts arise from the macrophage lineage, and their differentiation is dependent on RANKL, a member of the TNF family of cytokines. Here, we have provided ev...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5373870/ https://ncbi.nlm.nih.gov/pubmed/28287403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI90527 |
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