Kinase-independent functions of RIPK1 regulate hepatocyte survival and liver carcinogenesis

The mechanisms that regulate cell death and inflammation play an important role in liver disease and cancer. Receptor-interacting protein kinase 1 (RIPK1) induces apoptosis and necroptosis via kinase-dependent mechanisms and exhibits kinase-independent prosurvival and proinflammatory functions. Here...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Asıl Yazarlar: Van, Trieu-My, Polykratis, Apostolos, Straub, Beate Katharina, Kondylis, Vangelis, Papadopoulou, Nikoletta, Pasparakis, Manolis
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5490752/
https://ncbi.nlm.nih.gov/pubmed/28628031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI92508
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