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Kinase-independent functions of RIPK1 regulate hepatocyte survival and liver carcinogenesis
The mechanisms that regulate cell death and inflammation play an important role in liver disease and cancer. Receptor-interacting protein kinase 1 (RIPK1) induces apoptosis and necroptosis via kinase-dependent mechanisms and exhibits kinase-independent prosurvival and proinflammatory functions. Here...
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| Pubblicato in: | J Clin Invest |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5490752/ https://ncbi.nlm.nih.gov/pubmed/28628031 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI92508 |
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