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Test and Evaluation of ff99IDPs Force Field for Intrinsically Disordered Proteins

Over 40% eukaryotic proteomic sequences have been predicted as intrinsically disordered proteins (IDPs) or intrinsically disordered regions (IDRs) and confirmed to be associated with many diseases. However, widely used force fields could not well reproduce the conformers of IDPs. A previously ff99ID...

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Detalhes bibliográficos
Publicado no:J Chem Inf Model
Main Authors: Ye, Wei, Ji, Dingjue, Wang, Wei, Luo, Ray, Chen, Hai-Feng
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5490450/
https://ncbi.nlm.nih.gov/pubmed/25919886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.5b00043
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