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ff14IDPs Force Field Improving the Conformation Sampling of Intrinsically Disordered Proteins

Intrinsically disordered proteins (IDPs) are proteins which lack of specific tertiary structure and unable to fold spontaneously without the partner binding. These IDPs are found to associate with various diseases, such as diabetes, cancer, and neurodegenerative diseases. However, current widely use...

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Bibliographische Detailangaben
Veröffentlicht in:Chem Biol Drug Des
Hauptverfasser: Song, Dong, Wang, Wei, Ye, Wei, Ji, Dingjue, Luo, Ray, Chen, Hai-Feng
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5480619/
https://ncbi.nlm.nih.gov/pubmed/27484738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.12832
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