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Test and Evaluation of ff99IDPs Force Field for Intrinsically Disordered Proteins

Over 40% eukaryotic proteomic sequences have been predicted as intrinsically disordered proteins (IDPs) or intrinsically disordered regions (IDRs) and confirmed to be associated with many diseases. However, widely used force fields could not well reproduce the conformers of IDPs. A previously ff99ID...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Chem Inf Model
Egile Nagusiak: Ye, Wei, Ji, Dingjue, Wang, Wei, Luo, Ray, Chen, Hai-Feng
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5490450/
https://ncbi.nlm.nih.gov/pubmed/25919886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.5b00043
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