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IDP-Specific Force Field ff14IDPSFF Improves the Conformer Sampling of Intrinsically Disordered Proteins

Intrinsically disordered proteins (IDPs) or intrinsically disordered regions have not fixed tertiary structure, but play key roles in signal regulation, molecule recognition, and drug target. However it is difficult to study the structure and function of IDPs by traditional experimental methods beca...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Chem Inf Model
Main Authors: Song, Dong, Luo, Ray, Chen, Hai-Feng
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5731455/
https://ncbi.nlm.nih.gov/pubmed/28448138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.7b00135
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