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IDP-Specific Force Field ff14IDPSFF Improves the Conformer Sampling of Intrinsically Disordered Proteins

Intrinsically disordered proteins (IDPs) or intrinsically disordered regions have not fixed tertiary structure, but play key roles in signal regulation, molecule recognition, and drug target. However it is difficult to study the structure and function of IDPs by traditional experimental methods beca...

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Vydáno v:J Chem Inf Model
Hlavní autoři: Song, Dong, Luo, Ray, Chen, Hai-Feng
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5731455/
https://ncbi.nlm.nih.gov/pubmed/28448138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.7b00135
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