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Lyn kinase enhanced hepatic fibrosis by modulating the activation of hepatic stellate cells

The non-selectivity of tyrosine kinase inhibitors is the leading cause of drug withdrawals, and limits their application in anti-fibrosis. The role of Src tyrosine kinase Lyn in hepatic fibrosis remains elusive. In this study, we aimed to elucidate the role of Lyn kinase in the pathogenesis of hepat...

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Pubblicato in:Am J Transl Res
Autori principali: Li, Yin, Xiong, Lin, Gong, Jianping
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489887/
https://ncbi.nlm.nih.gov/pubmed/28670375
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