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Lyn kinase enhanced hepatic fibrosis by modulating the activation of hepatic stellate cells

The non-selectivity of tyrosine kinase inhibitors is the leading cause of drug withdrawals, and limits their application in anti-fibrosis. The role of Src tyrosine kinase Lyn in hepatic fibrosis remains elusive. In this study, we aimed to elucidate the role of Lyn kinase in the pathogenesis of hepat...

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Detalles Bibliográficos
Publicado en:Am J Transl Res
Main Authors: Li, Yin, Xiong, Lin, Gong, Jianping
Formato: Artigo
Idioma:Inglês
Publicado: e-Century Publishing Corporation 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489887/
https://ncbi.nlm.nih.gov/pubmed/28670375
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