Pyruvate Kinase M2 Tetramerization Protects against Hepatic Stellate Cell Activation and Liver Fibrosis

Liver fibrosis is an increasing health problem worldwide, for which no effective antifibrosis drugs are available. Although the involvement of aerobic glycolysis in hepatic stellate cell (HSC) activation has been reported, the role of pyruvate kinase M2 (PKM2) in liver fibrogenesis still remains unk...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Am J Pathol
Päätekijät: Zheng, Dandan, Jiang, Yuchuan, Qu, Chen, Yuan, Hui, Hu, Kaishun, He, Lu, Chen, Peng, Li, Jinying, Tu, Mengxian, Lin, Lehang, Chen, Hengxing, Lin, Zelong, Lin, Wenyu, Fan, Jun, Cheng, Guohua, Hong, Jian
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Investigative Pathology 2020
Aiheet:
Regular Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7786052/
https://ncbi.nlm.nih.gov/pubmed/32805235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2020.08.002
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