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Kinetics are probe-dependent during downhill folding of an engineered λ(6–85) protein
The Y22W/Q33Y/G46,48A mutant of the protein λ(6–85) folds in a few microseconds at room temperature. We find that its folding kinetics are probe-dependent under a strong bias toward the native state, a new signature for downhill folding. The IR- and fluorescence-detected relaxation time scales conve...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC548978/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15699334/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0409270102 |
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