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Kinetics are probe-dependent during downhill folding of an engineered λ(6–85) protein

The Y22W/Q33Y/G46,48A mutant of the protein λ(6–85) folds in a few microseconds at room temperature. We find that its folding kinetics are probe-dependent under a strong bias toward the native state, a new signature for downhill folding. The IR- and fluorescence-detected relaxation time scales conve...

詳細記述

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書誌詳細
主要な著者: Ma, Hairong, Gruebele, Martin
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC548978/
https://ncbi.nlm.nih.gov/pubmed/15699334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409270102
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