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Engineering Folding Dynamics from Two-State to Downhill: Application to λ-Repressor
[Image: see text] One strategy for reaching the downhill folding regime, primarily exploited for the λ(6–85) protein fragment, consists of cumulatively introducing mutations that speed up folding. This is an experimentally demanding process where chemical intuition usually serves as a guide for the...
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| Главные авторы: | , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Chemical
Society
2013
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| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3840902/ https://ncbi.nlm.nih.gov/pubmed/24079652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp405904g |
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