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Direct Observation of Downhill Folding of λ-Repressor in a Microfluidic Mixer
The protein λ(6-85) has been implicated in barrierless folding by observations of kinetic relaxation after nanosecond T-jump. In this work we observed folding of this protein after dilution of a high denaturant in an ultrarapid microfluidic mixer at temperatures far below the thermal midpoint. The o...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Biophysical Society
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2749784/ https://ncbi.nlm.nih.gov/pubmed/19751683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.07.003 |
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