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Engineering Folding Dynamics from Two-State to Downhill: Application to λ-Repressor

[Image: see text] One strategy for reaching the downhill folding regime, primarily exploited for the λ(6–85) protein fragment, consists of cumulatively introducing mutations that speed up folding. This is an experimentally demanding process where chemical intuition usually serves as a guide for the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Carter, James W., Baker, Christopher M., Best, Robert B., De Sancho, David
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Chemical Society 2013
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840902/
https://ncbi.nlm.nih.gov/pubmed/24079652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp405904g
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