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Comprehensive characterization of genes associated with the TP53 signal transduction pathway in various tumors

The TP53 signal transduction pathway is an attractive target for cancer treatments. In this study, we conducted a comprehensive molecular evaluation of 907 patients with cancer in Japan to identify genomic alterations in the TP53 pathway. TP53 mutations were frequently detected in many cancers, exce...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biochem
Main Authors: Ohnami, Shumpei, Ohshima, Keiichi, Nagashima, Takeshi, Urakami, Kenichi, Shimoda, Yuji, Saito, Junko, Naruoka, Akane, Hatakeyama, Keiichi, Mochizuki, Tohru, Serizawa, Masakuni, Ohnami, Sumiko, Kusuhara, Masatoshi, Yamaguchi, Ken
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487743/
https://ncbi.nlm.nih.gov/pubmed/28258440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-017-2977-1
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