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Comprehensive characterization of genes associated with the TP53 signal transduction pathway in various tumors
The TP53 signal transduction pathway is an attractive target for cancer treatments. In this study, we conducted a comprehensive molecular evaluation of 907 patients with cancer in Japan to identify genomic alterations in the TP53 pathway. TP53 mutations were frequently detected in many cancers, exce...
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| Udgivet i: | Mol Cell Biochem |
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| Main Authors: | , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer US
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5487743/ https://ncbi.nlm.nih.gov/pubmed/28258440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-017-2977-1 |
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