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Mutational burden and signatures in 4000 Japanese cancers provide insights into tumorigenesis and response to therapy
Tumor mutational burden (TMB) and mutational signatures reflect the process of mutation accumulation in cancer. However, the significance of these emerging characteristics remains unclear. In the present study, we used whole‐exome sequencing to analyze the TMB and mutational signature in solid tumor...
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| Vydáno v: | Cancer Sci |
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| Hlavní autoři: | , , , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
John Wiley and Sons Inc.
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6676127/ https://ncbi.nlm.nih.gov/pubmed/31152682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14087 |
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