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Comprehensive characterization of genes associated with the TP53 signal transduction pathway in various tumors

The TP53 signal transduction pathway is an attractive target for cancer treatments. In this study, we conducted a comprehensive molecular evaluation of 907 patients with cancer in Japan to identify genomic alterations in the TP53 pathway. TP53 mutations were frequently detected in many cancers, exce...

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Detalhes bibliográficos
Publicado no:Mol Cell Biochem
Main Authors: Ohnami, Shumpei, Ohshima, Keiichi, Nagashima, Takeshi, Urakami, Kenichi, Shimoda, Yuji, Saito, Junko, Naruoka, Akane, Hatakeyama, Keiichi, Mochizuki, Tohru, Serizawa, Masakuni, Ohnami, Sumiko, Kusuhara, Masatoshi, Yamaguchi, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487743/
https://ncbi.nlm.nih.gov/pubmed/28258440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-017-2977-1
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