Driver gene alterations and activated signaling pathways toward malignant progression of gastrointestinal stromal tumors

Mutually exclusive KIT and PDGFRA mutations are considered to be the earliest events in gastrointestinal stromal tumors (GIST), but insufficient for their malignant progression. Herein, we aimed to identify driver genes and signaling pathways relevant to GIST progression. We investigated genetic pro...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Cancer Sci
Main Authors: Ohshima, Keiichi, Fujiya, Keiichi, Nagashima, Takeshi, Ohnami, Sumiko, Hatakeyama, Keiichi, Urakami, Kenichi, Naruoka, Akane, Watanabe, Yuko, Moromizato, Sachi, Shimoda, Yuji, Ohnami, Shumpei, Serizawa, Masakuni, Akiyama, Yasuto, Kusuhara, Masatoshi, Mochizuki, Tohru, Sugino, Takashi, Shiomi, Akio, Tsubosa, Yasuhiro, Uesaka, Katsuhiko, Terashima, Masanori, Yamaguchi, Ken
פורמט: Artigo
שפה:Inglês
יצא לאור: John Wiley and Sons Inc. 2019
נושאים:
Original Articles
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6890443/
https://ncbi.nlm.nih.gov/pubmed/31553483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14202
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