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Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities

Chemokines function via G-protein coupled receptors in a robust network to recruit immune cells to sites of inflammation. Due to the complexity of this network, targeting single chemokines or receptors has not been successful in inflammatory disease. Dog tick saliva contains polyvalent CC-chemokine...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Singh, Kamayani, Davies, Graham, Alenazi, Yara, Eaton, James R. O., Kawamura, Akane, Bhattacharya, Shoumo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487423/
https://ncbi.nlm.nih.gov/pubmed/28655871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04378-1
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