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Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities

Chemokines function via G-protein coupled receptors in a robust network to recruit immune cells to sites of inflammation. Due to the complexity of this network, targeting single chemokines or receptors has not been successful in inflammatory disease. Dog tick saliva contains polyvalent CC-chemokine...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Singh, Kamayani, Davies, Graham, Alenazi, Yara, Eaton, James R. O., Kawamura, Akane, Bhattacharya, Shoumo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487423/
https://ncbi.nlm.nih.gov/pubmed/28655871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04378-1
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