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Environmental change drives accelerated adaptation through stimulated copy number variation

Copy number variation (CNV) is rife in eukaryotic genomes and has been implicated in many human disorders, particularly cancer, in which CNV promotes both tumorigenesis and chemotherapy resistance. CNVs are considered random mutations but often arise through replication defects; transcription can in...

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Bibliografische gegevens
Gepubliceerd in:PLoS Biol
Hoofdauteurs: Hull, Ryan M., Cruz, Cristina, Jack, Carmen V., Houseley, Jonathan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5486974/
https://ncbi.nlm.nih.gov/pubmed/28654659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2001333
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