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Environmental change drives accelerated adaptation through stimulated copy number variation
Copy number variation (CNV) is rife in eukaryotic genomes and has been implicated in many human disorders, particularly cancer, in which CNV promotes both tumorigenesis and chemotherapy resistance. CNVs are considered random mutations but often arise through replication defects; transcription can in...
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| Published in: | PLoS Biol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Public Library of Science
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5486974/ https://ncbi.nlm.nih.gov/pubmed/28654659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2001333 |
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