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Environmental change drives accelerated adaptation through stimulated copy number variation

Copy number variation (CNV) is rife in eukaryotic genomes and has been implicated in many human disorders, particularly cancer, in which CNV promotes both tumorigenesis and chemotherapy resistance. CNVs are considered random mutations but often arise through replication defects; transcription can in...

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Detaylı Bibliyografya
Yayımlandı:PLoS Biol
Asıl Yazarlar: Hull, Ryan M., Cruz, Cristina, Jack, Carmen V., Houseley, Jonathan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5486974/
https://ncbi.nlm.nih.gov/pubmed/28654659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2001333
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