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Environmental change drives accelerated adaptation through stimulated copy number variation

Copy number variation (CNV) is rife in eukaryotic genomes and has been implicated in many human disorders, particularly cancer, in which CNV promotes both tumorigenesis and chemotherapy resistance. CNVs are considered random mutations but often arise through replication defects; transcription can in...

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Detalles Bibliográficos
Publicado en:PLoS Biol
Main Authors: Hull, Ryan M., Cruz, Cristina, Jack, Carmen V., Houseley, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5486974/
https://ncbi.nlm.nih.gov/pubmed/28654659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2001333
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