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Environmental change drives accelerated adaptation through stimulated copy number variation

Copy number variation (CNV) is rife in eukaryotic genomes and has been implicated in many human disorders, particularly cancer, in which CNV promotes both tumorigenesis and chemotherapy resistance. CNVs are considered random mutations but often arise through replication defects; transcription can in...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:PLoS Biol
Main Authors: Hull, Ryan M., Cruz, Cristina, Jack, Carmen V., Houseley, Jonathan
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5486974/
https://ncbi.nlm.nih.gov/pubmed/28654659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2001333
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