Adaptive Evolution of UGT2B17 Copy-Number Variation

The human UGT2B17 gene varies in copy number from zero to two per individual and also differs in mean number between populations from Africa, Europe, and East Asia. We show that such a high degree of geographical variation is unusual and investigate its evolutionary history. This required first rein...

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Detalhes bibliográficos
Main Authors: Xue, Yali, Sun, Donglin, Daly, Allan, Yang, Fengtang, Zhou, Xue, Zhao, Mengyao, Huang, Ni, Zerjal, Tatiana, Lee, Charles, Carter, Nigel P., Hurles, Matthew E., Tyler-Smith, Chris
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556428/
https://ncbi.nlm.nih.gov/pubmed/18760392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2008.08.004
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