Adaptive Evolution of UGT2B17 Copy-Number Variation

The human UGT2B17 gene varies in copy number from zero to two per individual and also differs in mean number between populations from Africa, Europe, and East Asia. We show that such a high degree of geographical variation is unusual and investigate its evolutionary history. This required first rein...

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Bibliographic Details
Main Authors:	Xue, Yali, Sun, Donglin, Daly, Allan, Yang, Fengtang, Zhou, Xue, Zhao, Mengyao, Huang, Ni, Zerjal, Tatiana, Lee, Charles, Carter, Nigel P., Hurles, Matthew E., Tyler-Smith, Chris
Format:	Artigo
Language:	Inglês
Published:	Elsevier 2008
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2556428/ https://ncbi.nlm.nih.gov/pubmed/18760392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2008.08.004
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Adaptive Evolution of UGT2B17 Copy-Number Variation

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