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Copy number variation and evolution in humans and chimpanzees

Copy number variants (CNVs) underlie many aspects of human phenotypic diversity and provide the raw material for gene duplication and gene family expansion. However, our understanding of their evolutionary significance remains limited. We performed comparative genomic hybridization on a single human...

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Autors principals: Perry, George H., Yang, Fengtang, Marques-Bonet, Tomas, Murphy, Carly, Fitzgerald, Tomas, Lee, Arthur S., Hyland, Courtney, Stone, Anne C., Hurles, Matthew E., Tyler-Smith, Chris, Eichler, Evan E., Carter, Nigel P., Lee, Charles, Redon, Richard
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577862/
https://ncbi.nlm.nih.gov/pubmed/18775914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.082016.108
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