Copy number variation and evolution in humans and chimpanzees

Copy number variants (CNVs) underlie many aspects of human phenotypic diversity and provide the raw material for gene duplication and gene family expansion. However, our understanding of their evolutionary significance remains limited. We performed comparative genomic hybridization on a single human...

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Autores principales: Perry, George H., Yang, Fengtang, Marques-Bonet, Tomas, Murphy, Carly, Fitzgerald, Tomas, Lee, Arthur S., Hyland, Courtney, Stone, Anne C., Hurles, Matthew E., Tyler-Smith, Chris, Eichler, Evan E., Carter, Nigel P., Lee, Charles, Redon, Richard
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577862/
https://ncbi.nlm.nih.gov/pubmed/18775914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.082016.108
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