Copy number variation and evolution in humans and chimpanzees

Copy number variants (CNVs) underlie many aspects of human phenotypic diversity and provide the raw material for gene duplication and gene family expansion. However, our understanding of their evolutionary significance remains limited. We performed comparative genomic hybridization on a single human...

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Autori principali: Perry, George H., Yang, Fengtang, Marques-Bonet, Tomas, Murphy, Carly, Fitzgerald, Tomas, Lee, Arthur S., Hyland, Courtney, Stone, Anne C., Hurles, Matthew E., Tyler-Smith, Chris, Eichler, Evan E., Carter, Nigel P., Lee, Charles, Redon, Richard
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577862/
https://ncbi.nlm.nih.gov/pubmed/18775914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.082016.108
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