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A robust statistical method for case-control association testing with copy number variation
Copy number variation (CNV) is pervasive in the human genome and can play a causal role in genetic diseases. The functional impact of CNV cannot be fully captured through linkage disequilibrium with SNPs. These observations motivate the development of statistical methods for performing direct CNV as...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2784596/ https://ncbi.nlm.nih.gov/pubmed/18776912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.206 |
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