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A robust statistical method for case-control association testing with copy number variation

Copy number variation (CNV) is pervasive in the human genome and can play a causal role in genetic diseases. The functional impact of CNV cannot be fully captured through linkage disequilibrium with SNPs. These observations motivate the development of statistical methods for performing direct CNV as...

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Detaylı Bibliyografya
Asıl Yazarlar: Barnes, Chris, Plagnol, Vincent, Fitzgerald, Tomas, Redon, Richard, Marchini, Jonathan, Clayton, David, Hurles, Matthew E
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784596/
https://ncbi.nlm.nih.gov/pubmed/18776912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.206
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