Human cyclophilin 40 unravels neurotoxic amyloids

The accumulation of amyloidogenic proteins is a pathological hallmark of neurodegenerative disorders. The aberrant accumulation of the microtubule associating protein tau (MAPT, tau) into toxic oligomers and amyloid deposits is a primary pathology in tauopathies, the most common of which is Alzheime...

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Bibliographic Details
Published in:PLoS Biol
Main Authors: Baker, Jeremy D., Shelton, Lindsey B., Zheng, Dali, Favretto, Filippo, Nordhues, Bryce A., Darling, April, Sullivan, Leia E., Sun, Zheying, Solanki, Parth K., Martin, Mackenzie D., Suntharalingam, Amirthaa, Sabbagh, Jonathan J., Becker, Stefan, Mandelkow, Eckhard, Uversky, Vladimir N., Zweckstetter, Markus, Dickey, Chad A., Koren, John, Blair, Laura J.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5486962/
https://ncbi.nlm.nih.gov/pubmed/28654636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2001336
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