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Acetylation mimic of lysine 280 exacerbates human Tau neurotoxicity in vivo
Dysfunction and accumulation of the microtubule-associated human Tau (hTau) protein into intraneuronal aggregates is observed in many neurodegenerative disorders including Alzheimer’s disease (AD). Reversible lysine acetylation has recently emerged as a post-translational modification that may play...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4778021/ https://ncbi.nlm.nih.gov/pubmed/26940749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22685 |
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