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Aβ(43) is neurotoxic and primes aggregation of Aβ(40) in vivo
The involvement of Amyloid-β (Aβ) in the pathogenesis of Alzheimer’s disease (AD) is well established. However, it is becoming clear that the amyloid load in AD brains consists of a heterogeneous mixture of Aβ peptides, implying that a thorough understanding of their respective role and toxicity is...
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| Publié dans: | Acta Neuropathol |
|---|---|
| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Springer Berlin Heidelberg
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4469414/ https://ncbi.nlm.nih.gov/pubmed/25862636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-015-1419-y |
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