Human cyclophilin 40 unravels neurotoxic amyloids

The accumulation of amyloidogenic proteins is a pathological hallmark of neurodegenerative disorders. The aberrant accumulation of the microtubule associating protein tau (MAPT, tau) into toxic oligomers and amyloid deposits is a primary pathology in tauopathies, the most common of which is Alzheime...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Baker, Jeremy D., Shelton, Lindsey B., Zheng, Dali, Favretto, Filippo, Nordhues, Bryce A., Darling, April, Sullivan, Leia E., Sun, Zheying, Solanki, Parth K., Martin, Mackenzie D., Suntharalingam, Amirthaa, Sabbagh, Jonathan J., Becker, Stefan, Mandelkow, Eckhard, Uversky, Vladimir N., Zweckstetter, Markus, Dickey, Chad A., Koren, John, Blair, Laura J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5486962/
https://ncbi.nlm.nih.gov/pubmed/28654636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2001336
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