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Mechanism of intramembrane proteolysis investigated with purified rhomboid proteases
Intramembrane proteases have the unusual property of cleaving peptide bonds within the lipid bilayer, an environment not obviously suited to a water-requiring hydrolysis reaction. These enzymes include site-2 protease, γ-secretase/presenilin, signal peptide peptidase and the rhomboids, and they have...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC548647/ https://ncbi.nlm.nih.gov/pubmed/15616571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600537 |
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