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Mechanism of intramembrane proteolysis investigated with purified rhomboid proteases
Intramembrane proteases have the unusual property of cleaving peptide bonds within the lipid bilayer, an environment not obviously suited to a water-requiring hydrolysis reaction. These enzymes include site-2 protease, γ-secretase/presenilin, signal peptide peptidase and the rhomboids, and they have...
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| Publicat a: | EMBO J |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC548647/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15616571/ https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600537 |
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