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Targeting Autophagy in Cancer: Update on Clinical Trials and Novel Inhibitors

Eukaryotes use autophagy as a mechanism for maintaining cellular homeostasis by degrading and recycling organelles and proteins. This process assists in the proliferation and survival of advanced cancers. There is mounting preclinical evidence that targeting autophagy can enhance the efficacy of man...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Chude, Cynthia I., Amaravadi, Ravi K.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5486101/
https://ncbi.nlm.nih.gov/pubmed/28621712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18061279
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