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Targeting Autophagy in Cancer: Update on Clinical Trials and Novel Inhibitors

Eukaryotes use autophagy as a mechanism for maintaining cellular homeostasis by degrading and recycling organelles and proteins. This process assists in the proliferation and survival of advanced cancers. There is mounting preclinical evidence that targeting autophagy can enhance the efficacy of man...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Chude, Cynthia I., Amaravadi, Ravi K.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5486101/
https://ncbi.nlm.nih.gov/pubmed/28621712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18061279
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