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Targeting Autophagy in Cancer: Update on Clinical Trials and Novel Inhibitors

Eukaryotes use autophagy as a mechanism for maintaining cellular homeostasis by degrading and recycling organelles and proteins. This process assists in the proliferation and survival of advanced cancers. There is mounting preclinical evidence that targeting autophagy can enhance the efficacy of man...

詳細記述

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書誌詳細
出版年:Int J Mol Sci
主要な著者: Chude, Cynthia I., Amaravadi, Ravi K.
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5486101/
https://ncbi.nlm.nih.gov/pubmed/28621712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18061279
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