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Targeting Autophagy in Cancer: Recent Advances and Future Directions

Autophagy, a multistep lysosomal degradation pathway that supports nutrient recycling and metabolic adaptation, has been implicated as a process that regulates cancer. Although autophagy induction may limit the development of tumors, evidence in mouse models demonstrates that autophagy inhibition ca...

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Detalhes bibliográficos
Publicado no:Cancer Discov
Main Authors: Amaravadi, Ravi K., Kimmelman, Alec C., Debnath, Jayanta
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7306856/
https://ncbi.nlm.nih.gov/pubmed/31434711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-19-0292
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